Western University, Canada - London Ontario

| Saturday April 19, 2014
11:05 AM

Neurology - Area of Focus

Academic Appointment

Professor of Neurology and Epidemiology, Western University; Distinguished University Professor

Bio Sketch

Dr. Hachinski received his MD from the University of Toronto. After completing his residency training at the same university, Dr. Hachinski undertook a Cerebrovascular Laboratory fellowship at the National Hospital for Nervous Diseases at Queen Square in London, England and a research fellowship at Bispebjerg Hospital in Copenhagen, Denmark.

Dr. Hachinski is Professor of Neurology and Distinguished University Professor at Western University, Founding Chairman of the International Society for Vascular Behavioural and Cognitive Disorders, and President of the World Federation of Neurology, 2010 to the present. He founded, with John W. Norris the first sucessful acute stroke unit which has become the standard of care. An international expert on stroke prevention, he introduced the concepts and terms for multi-infarct dementia, leukoaraiosis and vascular cognitive impairment as well as devised the Ischemic Score, which remains the standard for identifying a vascular (treatable) component in cognitive impairment.

He was Editor-in-Chief of Stroke Journal, the leading publication in the field for an unprecedented 10 year term from 2000-2010. He has contributed to over 600 book chapters, scientific papers, editorials and other scholarly publications. He is the author, co-author or editor or co-editor of 17 books including Stroke: A Comprehensive Guide to Brain Attack, co-authored with his daughter Larissa Hachinski, which was written to increase public awareness of "brain attacks," a term coined by Dr. Hachinski to help drive home the urgency of strokes.

He has received 4 honorary doctorates. He has also received the Mihara International Award, Order of Canada, World Stroke Organization Leadership in Stroke Medicine Award, the Premier's Discovery Award in the Life Sciences and Medicine for "ground breaking research on relationship between stroke and Alzheimer disease". He was awarded the 2011 International BIAL Merit Award in Medical Sciences for a monograph on "The Long Fuse: Silent Strokes and Insidious Alzheimer Disease" and in 2012 a Doctor honoris causa from the Russian Academy of Medical Sciences. In 2013, Dr. Hachinski received the Order of Ontario and is the recipient of Queen Elizabeth II Diamond Jubilee Medal. Dr Hachinski was the 2013 Paddison Lecturer and was awarded the Chancellor's Award Lecture in Neuroscience and Neurology for his "contributions to neurological sciences and for outstanding academic leadership". Dr. Hachinski is the President of the World Federation of Neurology and the Founding Chair, Working Group, World Brain Alliance.
 

Research

Dr. Hachinski coordinates a group involved in experimental and population studies in the prevention of stroke and delay of stroke and Alzheimer's disease in collaboration with David F. Cechetto and Shawn Whitehead of Western's Department of Anatomy and Cell Biology. They have observed with the use animal models that levels of protein amyloid increases and causes inflammation and damage when a stroke is produced. To combat this, they are researching drugs that can be given to reduce inflammation and amyloid deposits to prevent the development of Alzheimer's after a stroke.  Alexander Thiel (Montreal) has begun studies in patients to confirm their experimental findings.

Clinical Trials

Dr. Hachinski's research also includes stroke risk factor controls. He is co-principal investigator with Cheryl Mayer of a Canada wide CIHR funded multi-center study led by  Richard Chan, using trained volunteers to work with high-risk patients for better control of blood pressure and other vascular risk factors.

Population Studies

Executive dysfunction as an early warning system of preventable cognitive decline.
Collaborator: Miia Kivipelto – Karolinska Institute, Stockholm, Sweden.

Population Screening

Studies of electronic versions of the Montreal Cognitive Assessment tool (MoCA) and the ischemic score
Collaborators: Ziad Nasreddine, inventor of MoCA (Montreal), Anne Snowdon, Chair, International Centre for Health Innovation, Richard Ivey Business School.

Vladimir Hachinski

Medical Interests

  • Alzheimer's Disease
  • Stroke Prevention

Office Contact Information

  • Phone:519 - 663 - 3624
  • Fax:519 - 663 - 3910
  • Address:

London Health Sciences Centre
University Hospital
339 Windermere Road
London Ontario Canada
N6A 5A5