Western University, Canada - London Ontario

| Tuesday October 21, 2014
6:20 PM

Neurology - Area of Focus

Academic Appointment

Professor of Neurology and Epidemiology, Western University; Distinguished University Professor

Bio Sketch

NEUROLOGY – AREAS OF FOCUS
Stroke, Preventable Dementias, World Neurology

BIO SKETCH
Dr. Vladimir Hachinski received his MD from the University of Toronto. After completing his residency training at the same university, he undertook a Cerebrovascular Laboratory fellowship at the National Hospital for Nervous Diseases at Queen Square in London, England and a research fellowship at Bispebjerg Hospital in Copenhagen, Denmark.

Dr. Hachinski is Professor of Neurology and Distinguished University Professor at Western University, He founded, with John W. Norris the first successful acute stroke unit which has become the standard of care and with David Cechetto discovered the key role of the insula of the brain in mediating sudden death. He introduced the concepts and terms multi-infarct dementia, leukoaraiosis and vascular cognitive impairment and devised the Hachinski ischemic score, which remains the standard for identifying a vascular (treatable) component of cognitive impairment.

Dr. Hachinski was Editor-in-Chief of the journal Stroke, the leading publication in the field for an unprecedented 10 year term from 2000-2010. He introduced 9 international editions and a unique author mentorship program. He has contributed over 800 scientific papers, book chapters, editorials and other scholarly publications, with over 27,000 citations and an H-Index of 79. He is the author, co-author or editor or co-editor of 17 books including Stroke: A Comprehensive Guide to Brain Attack, co-authored with his daughter Larissa Hachinski, which was written to increase public awareness of brain attack, a term coined by Dr. Hachinski to help drive home the urgency of strokes.

He has received 4 honorary doctorates, the Mihara International Award, World Stroke Organization Leadership in Stroke Medicine Award, the Premier's Discovery Award in the Life Sciences and Medicine for "ground breaking research on relationship between stroke and Alzheimer disease". Dr. Hachinski was the founding Chair of the International Society for Vascular Behavioural and Cognitive Disorders and President of the World Federation of Neurology, 2010-2013. He is Vice President of the World Stroke Organization. He was awarded the 2011 International BIAL Merit Award in Medical Sciences for a monograph on "The Long Fuse: Silent Strokes and Insidious Alzheimer Disease" and in 2012 a Doctor honoris causa from the Russian Academy of Medical Sciences. In 2008 he received the Order of Canada and in 2013 the Order of Ontario and the Queen Elizabeth II Diamond Jubilee Medal. He was the 2013 Paddison Lecturer and was awarded the Chancellor's Award Lecture in Neuroscience and Neurology for his "contributions to neurological sciences and for outstanding academic leadership" at the University of Louisiana. Dr. Hachinski was the Allan & Maria Myers International Visiting Fellow for 2014 at the Florey Institute in Melbourne, Australia and was the 2014 Brain Scholar, Cambridge, Oxford and London UK Universities.

Research

Dr. Hachinski coordinates a group involved in experimental, clinical and population studies in the prevention of stroke and delay of Alzheimer disease.
Experimental
With David F. Cechetto and Shawn Whitehead of Western's Department of Anatomy and Cell Biology, he observed in Alzheimer animal models that the presence of the protein amyloid is associated with inflammation and brain damage when a stroke is induced and that this can be prevented with anti-inflammatory drugs. Alexander Thiel (Montreal) has begun studies in patients to confirm their experimental findings.


Clinical Trials

The PARTNERS Study

He is co-principal investigator of a Canada wide CIHR funded multi-center study led by Richard Chan, using trained volunteers to work with high-risk patients for better control of blood pressure and other vascular risk factors to prevent stroke and cognitive decline.


Population

Executive dysfunction as an early warning system of stroke and preventable cognitive decline.
Collaborators: Miia Kivipelto, Karolinska Institute, Stockholm, Sweden; David Bennett, Rush University, Chicago.


Studies of electronic versions of the Montreal Cognitive Assessment tool (MoCA) and the Hachinski ischemic score.
Collaborators: Ziad Nasreddine, inventor of MoCA (Montreal), Anne Snowdon, Chair, International Centre for Health Innovation, Richard Ivey Business School, William Shankle, Cognitive Science Department, University of California, Irvine.


Neuroscience

Handedness and brain patterns of cardiovascular control
Collaborators: David Cechetto, Department of Anatomy and Cell Biology, Western University, Kevin Shoemaker, Faculty of Health Sciences, Western University, Mark Daley, Faculty of Science, Western University

The brain and rhythm preferences: Constants and variations, implications and applications
Collaborators: Jessica Grahn, Faculty of Social Science, Department of Psychology, Western University, Jason Stanford, Don Wright Faculty of Music, Western University, Betty Anne Younker, Dean of the Don Wright Faculty of Music, Western University based on a Dream Waltz by Hachinski and Jason Stanford, premiered at the Musikverein in Vienna, Austria, September 24, 2013.


RESEARCH OPPORTUNITIES

Research projects for residents in neurology and fellowships for those who have completed their training are available. Contact:

 

Vladimir Hachinski

Medical Interests

  • Dementia
  • Alzheimer's Disease
  • Stroke Prevention

Office Contact Information

  • Phone:519 - 663 - 3624
  • Fax:519 - 663 - 3910
  • Address:

London Health Sciences Centre
University Hospital
339 Windermere Road
London Ontario Canada
N6A 5A5