Western University, Canada - London Ontario

| Wednesday September 3, 2014
12:34 AM

Neurology - Area of Focus

Academic Appointment

Associate Professor of Neurology, Western University

Bio Sketch

Dr. Nicolle received his MD from Western University in 1985. He completed a neurology residency at Western University (1990) followed by a Canadian Medical Research Council (MRC) Scholarship at the Institute of Molecular Medicine, University of Oxford, U.K, where he received his D. Phil/PhD (1994). His research in Oxford was on the cellular immunology and antigen-specific immunotherapy of myasthenia gravis.

Dr. Nicolle is currently an Associate Professor in the Department of Clinical Neurological Sciences at Western University. He is the Neuromuscular Group leader, director of the Myasthenia Gravis Clinic and also the director of the EMG Laboratory at the London Health Science Centre.
For the last several years he has been an examiner for the Royal College of Physicians and Surgeons of Canada (Neurology), and for the Canadian Society of Clinical Neurophysiologists (CSCN; EMG exam) for which he is currently the president of the EMG section. He is also as a member of Medical/Scientific Advisory Board of the Myasthenia Gravis Foundation of America. He was the founder and current president of the Canadian Neuromuscular Group, an affiliate society of the Canadian Neurological Sciences Federation (CNSF) and is the medical advisor for the Myasthenia Gravis Coalition of Canada (MGCC).

Dr. Nicolle is one of several consulting neurologists in the Neuromuscular Clinic at University Hospital, LHSC, all of who have subspecialty expertise in the diagnosis and management of patients with neuromuscular diseases. Although involved in the management of patients with neuromuscular diseases in general, his specific interest is in myasthenia gravis (MG) and other disorders of neuromuscular transmission including congenital myasthenic syndromes and the Lambert Eaton Myasthenic Syndrome. The MG clinic at LHSC, directed by Dr. Nicolle, actively follows several hundred patients with myasthenia gravis referred from a number of centers in Ontario and across Canada. Dr. Nicolle has extensive experience in the diagnosis and management of MG and is involved in research in this disease. His other areas of clinical expertise include paraneoplastic and autoimmune diseases of the peripheral nervous system.

Research

Dr. Nicolle's main research interests are in the field of myasthenia gravis. Current projects include clinical trials of therapies in MG, possible mechanisms of intravenous immunoglobulin (IVIg) and other clinical trials on immunosuppressive medications potentially useful for the treatment of MG. Collaborating with investigators in other centers including the University of Oxford, other studies have included those looking at mutations in congenital myasthenic syndromes, and anti-MuSK antibodies in seronegative myasthenia gravis. He is also involved in research in the EMG laboratory, including studies of single fibre EMG, and of the longitudinal changes in entrapment neuropathies.

Michael W. Nicolle

Medical Interests

  • Peripheral Nerve Diseases
  • Neuromuscular Disorders
  • Electromyography (EMG: diseases of peripheral nerve and muscle)
  • Neuromuscular Transmission

Office Contact Information

  • Phone:519 - 663 - 3236
  • Address:

London Health Sciences Centre
University Hospital
339 Windermere Road
London Ontario Canada
N6A 5A5