Western University, Canada - London Ontario

| Monday August 21, 2017
7:42 PM

Academic Appointment

Associate Professor of Neurosurgery, Western University

Bio Sketch

Dr. Megyesi received his MD from Western University in 1985. He completed a comprehensive surgical internship the same institution followed by a neurosurgical residency at the University of Alberta Hospitals in Edmonton. Following his training, Dr Megyesi completed fellowships at Harvard University and the University of Alberta.

Dr. Megyesi is currently Assistant Professor in the Division of Neurosurgery at Western University. He is also Director of Research in the Division of Neurosurgery, coordinator of Neurosurgery Residency Seminar Series and Board Member of Brain Tumor Tissue Bank.


Dr. Megyesi's clinical research interests focus on angiogenesis in brain tumors. A tumor's ability to grow is linked to its ability to recruit a supply of new blood vessels. In order to do this, it sends out "signals" to already existing blood vessels to sprout new branches to feed it. This is the process of angiogenesis. His past studies have investigated angiogenic growth factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF).

Dr. Megyesi's research interests also include cerebral vasospasm in the brain. Cerebral vasospasm is delayed-onset, prolonged and pathological cerebral arterial narrowing following aneurysmal subarachnoid hemorrhage (SAH). His past work has looked at the treatment of this disorder using transluminal balloon angioplasty in an animal model.

Joseph S. Megyesi

Medical Interests

  • Cerebral Vasospasm
  • HIV Neuropathology
  • Technical Aspects of Intracranial Surgery
  • Angiogenesis and Invasion of Brain Tumors
  • Imaging of Brain Tumors
  • Intratumoral Drug Delivery Systems for Malignant Brain Tumors
  • Molecular Signatures of Brain Tumors

Office Contact Information

  • Phone:519 - 663 - 3565
  • Address:

London Health Sciences Centre
University Hospital
339 Windermere Road
London Ontario Canada
N6A 5A5